pentobarbital will reduce the level or impact of voriconazole by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Mysterious.
pentobarbital will minimize the extent or influence of isavuconazonium sulfate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lower the level or outcome of solifenacin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital decreases effects of hemin by pharmacodynamic antagonism. Use Caution/Monitor. Drugs that improve delta-aminolevulinic acid synthetase may perhaps lessen hemin impact.
pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. May perhaps bring about loss of virologic reaction and doable resistance.
pentobarbital will lower the extent or outcome of celecoxib by influencing hepatic enzyme CYP2C9/ten metabolism. Small/Significance Mysterious.
pentobarbital will lower the level or influence of meloxicam by impacting hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Mysterious.
pentobarbital will decrease the extent or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital raises toxicity of methoxyflurane by rising metabolism. Contraindicated. Elevated metabolism of methoxyflurane to nephrotoxic compounds.
pentobarbital will decrease the extent or outcome of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lower the level or result of itraconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unidentified.
pentobarbital increases toxicity of buprenorphine, prolonged-performing injection by pharmacodynamic synergism. Modify Therapy/Check Closely. Coadministration of buprenorphine and benzodiazepines or other CNS depressants increases risk of adverse reactions including overdose, respiratory despair, and Demise. Cessation of benzodiazepines or other CNS depressants is desired in most cases.
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pentobarbital will decrease the level or influence of propafenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.